Abstract
Ethylcarboxylate and acetyl selenoloquinoline derivatives were prepared in a one pot synthesis via reaction of sodium hydrogen selenide and 2-chloro-3-cyano-4-methylquinoline followed by reactions with ethyl chloroacetate and chloro acetone respectively which used as precursors to synthesize many of tetra and pentacyclic systems. A new series of pyrimido [4 ',5 ':4,5]selenolo[2,3-b]quinoline, thiazino[2',3':4,5]selenolo[2,3-b]quinoline, oxazino[2',3':4,5]selenolo[3,2-b]quinoline, pyrido[2 ',3 ':4,5]selenolo[2,3-b]quinoline, pyrido[2 ',3 ':4,5]selenolo[2,3-b]quinoline-2-substituted selenyl and selenolo[2 ',3 ':5,6]pyrido[2 '',3 '':4,5]selenolo[2,3-b]quinoline derivatives were prepared. Elemental analysis, IR, H-1 NMR, C-13 NMR and mass spectra confirmed the structures of the newly synthesized compounds.
[GRAPHICS]
.