Abstract
A simple and mild synthesis of selenotheophyllines is described based on the reaction of 7-alkyl-8-chlorotheophylline with sodium hydrogenselenide followed by reactions with halocompounds such as chloroacetonitrile, ethyl chloroacetate, chloroacetamide, and ethyl chloroformate. Elemental analysis, infrared,
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H NMR,
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C NMR, and mass spectral data confirmed the structure of the newly synthesized compounds.