Abstract
Compounds 2-[1-(3,5-dimethylpyrazol-1-yl)ethyl]pyridine (L1) and 2-[1-(3,5-diphenylpyrazol-1-yl) ethyl]pyridine (L2) were obtained in a three-step procedure which involved the reduction of acetylpyridine using NaBH4, chlorination of the alcohol intermediate using SOCl2 and subsequent reaction with appropriate pyrazoles. Reactions of Ll and L2 with Ni(II) and Fe(II) halides produced the respective complexes Ni(L1)Br-2 (1), Ni(L1)Cl-2 (2), Fe(L1)Cl-2 (3) and Ni(L2)Br-2 (4) as racemic mixtures in moderate yields. The molecular structures of complexes 1 and 4 are dinuclear and mononuclear respectively. All the complexes (1-4) formed active catalysts for the transfer hydrogenation of ketones (THK) in 2-propanol at 82 degrees C affording conversions of 58%-84% within 48 h. The influence of catalyst structure, reaction conditions and identity of ketone substrates in the TH reactions have been successfully established. (C) 2017 Elsevier B.V. All rights reserved.