Abstract
Objective: The main objective of this research work is to find out the resistance of insulin in the patients suffering from infection of non-diabetic HCV with the utilization of the HOMA IR better acknowledged as homeostatic model assessment of insulin resistance.
Methodology: The patients found with anti HCV + were the part of this research work. Patients having type 2 diabetes, disorder of thyroid, the presence of the excess fat in the blood, hypercortisolism or some other disorder of infection were not the part of this research work. The record of the age of the patient, his weight, his age & on availability of diabetes maintained. Levels of the fasting glucose of the blood & insulin performed. Standard formulas were in use for the calculation of the BMI & resistance of the insulin. Patients found with resistance of insulin with the utilization of the standard formula HOMA IR of greater than 2.5 were well insulin resistant. SPSS V.18 was in use for the analysis of the collected information.
Results: Total 155 patients were the part of this case study. The calculation of the HOMA IR carried out on those patients and its average amount was 2.470 +/- 1.3. About fifty one percent (n: 79) found with HOMA IR >2.5 displaying the resistance to insulin.
Conclusion: In the under develop countries as Pakistan, the occurrence of HCV infection is very high, the outcome of these infections are not new. We found the resistance to insulin in 51.0% patients suffering from chronic HCV infection.