Abstract
Background: peptic ulcer disease [PUD] is open sores or erosions equal to or greater than 0.5 cm that develop in the lining mucosa of the esophagus, stomach and the upper portion of small intestine.
Aim: detection the relationship between the different risk factors and the development of peptic ulcer among male and female patients from 25 = 55 years.
Methods: This study is a cross-sectional questionnaire-based study that was conducted on 50 patients of peptic ulcer disease in outpatient department in King Khalid hospital and all of patients were diagnosed by endoscopy. The data was collected through a Questionnaire, by primary data from the patients.
Results: Our research results showed that females who have peptic ulcer are more than males where ratio is 3:2. H. pylori is the most common risk factor, it induced peptic ulcer in 60 % of patients. Stress induced PUD in 48 % of total patients. Using NSAIDs regularly induce peptic ulcer in 40 % of patients. Smoking comes at the last by 24 % in males and 0% in females. Most of male smoker patients were smoking for more than 10 years and represent 83.3 % of patients while 16.7 % from male smokers were smoking for 5-10 years. No cases of peptic ulcer observed and smoked less than 5 years smoking.
Conclusion: Peptic ulcer disease more common in females than males in this study and this may attributed to life style which makes women expose to physical and psychological stress. The H. pylori, NSAIDs and stress are most causes of the PUD in najran.