Abstract
Introduction: The acid peptic injury in the gastrointestinal tract is called peptic ulcer, it results from a rupture in the mucosa to the submucosa. Generally, most of the peptic ulcers locate in the stomach or in the duodenum in its proximal part, however, the may also locate in Meckel's diverticulum or in the oesophagus. In this review, we mean by the "peptic ulcer" term the ones in the stomach or duodenum.
Aim of work: In this review, we will discuss the recent strategies to diagnose and treat peptic ulcer disease.
Methodology: We did a systematic search for most recent evidence regarding the peptic ulcer disease diagnosis and treatment in the emergency department using PubMed search engine (http://www.ncbi.nlm.nih.gov/) and Google Scholar search engine (https://scholar.google.com). We only included full articles.
Conclusions: The quickly decreasing incidence and prevalence of infections with Helicobacter pylori along with the widespread increase of the use of strong anti-secretory agents can mean that peptic ulcers have become significantly less important concerns than they were twenty years ago. Management has become more difficult than before due to the increasing development of antibiotics resistance globally and the widespread increase in the administration of anti-thrombotic agents among the elderly.