Abstract
A PMR analytical method is developed for the quantitation of Clofibrate (ethyl 2-(ρ-chlorophenoxy)-2-methylpropionate) as a drug entity and in capsule dosage form. Standard deviations of ± 1. 07% and ± 1. 34% were obtained for the pure drug and capsules, respectively. The results obtained comply with official standards required by different pharmacopeias. The PMR spectrum, in addition, provides a very specific mean for identification of Clofibrate. The procedure proved to be simple, rapid, accurate and precise.