Abstract
Purpose: A wide range of posterior ophthalmic malformation is undervalued in the literature. This includes congenital cystic eye, microphthalmia and anophthalmia, Persistent Hyperplastic Primary Vitreous, and other retina disc anomalies. Moreover, there is a lack of regional data in the kingdom of Saudi Arabia regarding these anomalies. In this sense, the current study consists of a literature review and a case series of posterior ophthalmic malformation to see if there is any difference in the spectrum of pathology presentation in KSA compared to other regions.
Methods: Retrospective study reviewing medical records and histopathology finding looking for the spectrum of disease and presentation for patients with posterior ophthalmic malformations in King Abdulaziz University Hospital [KAUH] and King Khaled Eye Specialist Hospital [KKESH] from the period of [2000-2018].
Results: Total of seven out of twelve histopathologically confirmed cases of posterior ophthalmic malformation were included in this study. Charts revealed that most cases were females, and all of them presented unilateral anomalies. Family history, due to the high consanguinity rate in the studied population, revealed only one case of a patient with parents who were first degree relatives.
Conclusion: The current work adds a proper understanding of posterior ocular malformation pathological spectrum, together with the outcomes in KSA population to provide a better management and counseling.