Abstract
Common and novel synthesized active methylene compounds as well as some heterocycles bearing active methyl or having an active methine in their structures used for the syntheses of pyrazoles and pyrazolopyrimidines of expected medical and pharmaceutical importance. Many synthetic approaches were used for the syntheses of the target heterocyclic systems such as cyclocondensation reactions, ring opening-ring closure, cycloaddition, acid-, base-catalyzed reaction, intramolecular cyclization and self-condensation as well as ring-chain tautomersim has been discussed in this review. In addition, the antimicrobial activity and Mollucicidal activity of some newly synthesized pyrazoles and pyrazolopyrimidines compounds were deduced.