Abstract
(Aim) In order to detect pathological brains in a more efficient way, (Method) we proposed a novel system of pathological brain detection (PBD) that combined wavelet packet Tsallis entropy (WPTE), feedforward neural network (FNN), and real-coded biogeography-based optimization (RCBBO). (Results) The experiments showed the proposed WPTE + FNN + RCBBO approach yielded an average accuracy of 99.49% over a 255-image dataset. (Conclusions) The WPTE + FNN + RCBBO performed better than 10 state-of-the-art approaches.