Peptidoyl benzotriazoles permit the acylation of active methylene groups of nitriles to provide CH-acylated nitrile enols from alpha-amino acids or from di- or tripeptides with no loss of chirality.
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Title
Peptidoyl Benzotriazolide-Mediated Acylation of Nitrile-Activated Methylene Groups
Creators - without role
Sandhyamayee Sahu - University of Florida
Iryna O. Lebedyeva - University of Florida
Siva S. Panda - University of Florida
Alan R. Katritzky - University of Florida
Publication Details
Synthesis (Stuttgart), Vol.45(9), pp.1256-1260
Publisher
Thieme Medical Publishers
Number of pages
5
Grant note
University of Florida
Kenan Foundation
King Abdulaziz University, Jeddah, Saudi Arabia