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Peptidoyl Benzotriazolide-Mediated Acylation of Nitrile-Activated Methylene Groups
Journal article   Peer reviewed

Peptidoyl Benzotriazolide-Mediated Acylation of Nitrile-Activated Methylene Groups

Sandhyamayee Sahu, Iryna O. Lebedyeva, Siva S. Panda and Alan R. Katritzky
Synthesis (Stuttgart), Vol.45(9), pp.1256-1260
02/05/2013

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Peptidoyl benzotriazoles permit the acylation of active methylene groups of nitriles to provide CH-acylated nitrile enols from alpha-amino acids or from di- or tripeptides with no loss of chirality.

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