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PhI(OAc)(2) mediated an efficient Knoevenagel reaction and their synthetic application for coumarin derivatives
Journal article   Peer reviewed

PhI(OAc)(2) mediated an efficient Knoevenagel reaction and their synthetic application for coumarin derivatives

Danish Khan, Sayeed Mukhtar, Meshari A. Alsharif, Mohammed Issa Alahmdi and Naseem Ahmed
Tetrahedron letters, Vol.58(32), pp.3183-3187
09/08/2017
DOI: https://doi.org/10.1016/j.tetlet.2017.07.018

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
A phenyliododiacetate (PhI(OAc)(2)) mediated an efficient and novel protocol for the Knoevenagel reaction has been successfully accomplished. A base free, simple and straightforward method afforded wide substrate scope and good functional group tolerance, having high yields (80-92%) under environmentally benign and mild reaction conditions. (C) 2017 Elsevier Ltd. All rights reserved.

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