Abstract
Lohani, M., Ahmad, A.H., Singh, K.P. and Verma, S. 2010. Pharmacokinetics and residual studies of Florfenicol following multiple dose oral administration in poultry. J. Appl. Anim. Res., 38: 9-12.
Pharmacokinetics o f Florfenicol was established in the plasma of poultry. Florfenicol was given as multiple dose 30 mg.kg
−1
orally daily for 5 days in poultry. The mean values of half-life, body clearance (Cl
B
) and mean volume of distribution (Vd
area
) were 8.39 and 7.91 h; 0.5 and 0.29 l.h
−1
.kg
−1
and 4.8 and 2.70 l.kg
−1
after first and last dose, respectively. On the basis of depletion study for Florfenicol in poultry, a withdrawal time of 72 h was calculated.