Abstract
Clozapine drug is photo-stable under irradiation of light for a long time, so we can store it in difficult and hot conditions. In addition the activity of clozapine is inhibited of the absorption spectra in the presence of glucose and enhanced in the presence of iron(III). We succeeded in detecting the concentration of clozapine in the range 1-60 x 10(-9) M using Eu(III)-dipicolinic acid complex as photo probe type and using Stern-Volmer equation to determine the Stern-Volmer constant, critical radius and the mechanism of quenching of luminescence of Eu(III)-dipicolinic acid complex is found to be of dipolar-dipolar interaction. (C) 2009 Elsevier B.V. All rights reserved.