Abstract
The major aspects of using plant-derived medications are significantly safer and secure than synthetic ones. The n-hexane seed extract of ayurvedic medicinal plants
Myristica fragrans
was also utilized as food ingredients have analyzed for phytochemical existence by Gas Chromatography-mass spectrometry (GC–MS). Twenty-three phytoconstituents were identified with elemicin (24.44%) as the major constituent. Lipid peroxidase, catalase and DPPH assays were performed using the isolated elemicin and the results revealed significant antioxidant activity. The antibacterial study revealed that elemicin showed MIC of 31.25 μg/mL against
Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi,
and 62.5 μg/mL against
Klebsiella pneumonia
and
Staphylococcus aureus.
Elemicin exhibited better antifungal activity against
Candida tropicalis
and
Aspergillus flavus
than
Aspergillus niger, Penicillium chrysogenum
and
Trichophyton rubrum
. The study implies that the elemicin isolated from
Myristica fragrans
possess promising bioactive properties and can be crucially utilized in the development of therapeutic agents and food preservatives.