Abstract
The present study was conducted to evaluate phytochemicals, antimicrobial and antioxidant potential of Lagerstroemia indica L. The phytochemical screening of L. indica revealed the presence of active metabolites such as anthraquinones, reducing sugars, terpenoids, flavonoids, saponins, tannins, alkaloids and cardiac glycosides. Antimicrobial assessment was carried out against Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus), Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli) and fungal strains (Aspergillus oryzae and Aspergillus niger). Maximum antibacterial potential (58.33 +/- 0.88 mm) was exhibited by petroleum ether extract of bark against B. subtilis. The maximum antifungal potential 40.33 + 0.88 mm and 40.0 + 1.15 mm against A. niger was observed by chloroform extract of bark and fruits respectively. The antioxidant potential was assessed using five assays viz. ABTS activity, DPPH degrees radical scavenging activity, metal chelating activity, total flavonoid contents and total phenolic contents. Highest TEAC value 7.946 +/- 0.04 mM trolox for ABTS+ assay was observed by aquous extract of leaves. The highest values for total flavonoid contents 1185.740 +/- 0.01 mu g/ml and total phenolic contents 40.333 +/- 0.23 mu g/ml was exhibited by petroleum ether bark extract. The maximum metal chelating activity 60.302 +/- 0.93 was observed by petroleum ether extract of fruit. The highest value of % DPPH degrees (92.92 +/- 0.08 %) was observed by aquous extract of bark.