Abstract
3-hydroxy-1-methylene-2,3,4,4-tetrahydroxynapthalene-2-carbaldehyde (1), 22,23-dihydroxy spinasterol (2) were isolated from petroleum ether extrct of the fruits of Luffa cylindrical. The structures of the isolated compounds were elucidated by extensive spectroscopic studies including IR and high field NMR analysis. Petroleum ether extract (i.e. crude extract) exhibited mild to moderate antimicrobial activity. This is the first report of isolation of compound of 1 - 2 from this species.