Abstract
Pituitary metastases is a rare clinical diagnosis usually made in the setting of known primary systemic cancer with widespread metastasis to other organs. Pituitary metastases as the first manifestation of a still undiagnosed systemic cancer is much less frequent.
The cases of three patients harboring pituitary metastases are described. In two of them the pituitary tumor was the first manifestation of the systemic cancer and loss of visual acuity was the most common initial clinical sign.