Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors

Sunil K Singh; P. Ganapati Reddy; K SRINIVASA RAO; Braj B Lohray; P Misra; Shaikh A Rajjak; Yeleswarapu K Rao; A Venkateswarlu; Abdul Rajjak Shaikh

doi:10.1016/j.bmcl.2003.10.027

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Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors

Journal article

Peer reviewed

Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors

Sunil K Singh, P. Ganapati Reddy, K SRINIVASA RAO, Braj B Lohray, P Misra, Shaikh A Rajjak, Yeleswarapu K Rao, A Venkateswarlu and Abdul Rajjak Shaikh

Bioorganic & medicinal chemistry letters, Vol.14(2), pp.499-504

19/01/2004

DOI: https://doi.org/10.1016/j.bmcl.2003.10.027

PMID: 14698190

Abstract

Biological and medical sciences

Bones, joints and connective tissue. Antiinflammatory agents

Medical sciences

Pharmacology. Drug treatments

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Title: Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors
Creators - without role: Sunil K Singh - Dr. Reddy's Laboratories
P. Ganapati Reddy - Dr. Reddy's Laboratories
K SRINIVASA RAO - Discovery Chemistry, Discovery Research-Dr. Reddy's Laboratories Ltd, Bollaram Road, Miyapur, Hyderabad 500 049, India
Braj B Lohray - Dr. Reddy's Laboratories
P Misra - Dr. Reddy's Laboratories
Shaikh A Rajjak - Dr. Reddy's Laboratories
Yeleswarapu K Rao - Discovery Chemistry, Discovery Research-Dr. Reddy's Laboratories Ltd, Bollaram Road, Miyapur, Hyderabad 500 049, India
A Venkateswarlu - Dr. Reddy's Laboratories
Abdul Rajjak Shaikh - King Abdullah University of Science & Technology
Publication Details: Bioorganic & medicinal chemistry letters, Vol.14(2), pp.499-504
Publisher: Elsevier
Identifiers: 9945830708331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article