Abstract
Background:
Polycystic ovary syndrome (PCOS) is the major endocrine disorder in
women that promptly affects psychological perception and associated social and cultural relations
with women. Health-related quality of life (HRQOL) was assessed to explore the effects of PCOS
in terms of emotional aspects and related anxiety in women.
Objective:
The purpose of this study was to explore the psychological burden in adolescent women
due to PCOS.
Methods:
A prospective questionnaire-based study was conducted at a tertiary care hospital, and
100 PCOS and 200 healthy cases were enrolled based on Rotterdam criteria during the year 2017
and 2018. Pre-validated HRQOL questionnaires like Short Form Health survey-36 (SF-36) were
used for evaluating the impact of PCOS in women.
Results:
In PCOS cases, mean age and body mass index was 22.81±5.33 and 24.35±5.49 respectively.
A significant difference (P=0.001) regarding age was observed between PCOS and healthy
control. The higher percentage of PCOS cases (90 %) were among the category of less than 5 years of
PCOS symptoms. In addition, we observed a significant (P=0.001) reduction in quality of life in all
eight domains of SF-36 questionnaire between PCOS and healthy control cases. Moreover, a decreasing
pattern of SF-36 score was observed with an increase in the duration of PCOS symptoms.
Conclusion:
Altogether, our result of this study concluded that HRQOL especially emotional
changes were more affected in adolescent and middle age group patients that may be due to fear of
infertility and cosmetic problems.