Population Pharmacokinetics of Unbound and Total Drug Concentrations Following Intravenously Administered Carbamazepine in Elderly and Younger Adult Patients With Epilepsy

Journal article

Peer reviewed

Ghada F. Ahmed, Richard C. Brundage, Susan E. Marino, James C. Cloyd, Ilo E. Leppik, Page B. Pennell, R. Eugene Ramsay and Angela K. Birnbaum

Journal of clinical pharmacology, Vol.53(3), pp.276-284

03/2013

PMCID: PMC4900893

PMID: 23408495

Abstract

adults and elderly

carbamazepine

epilepsy

nonlinear mixed effects modeling

population pharmacokinetics

stable-labeled intravenous dosing

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Title: Population Pharmacokinetics of Unbound and Total Drug Concentrations Following Intravenously Administered Carbamazepine in Elderly and Younger Adult Patients With Epilepsy
Creators - without role: Ghada F. Ahmed - University of Minnesota
Richard C. Brundage - University of Minnesota
Susan E. Marino - University of Minnesota
James C. Cloyd - University of Minnesota
Ilo E. Leppik - University of Minnesota
Page B. Pennell - Brigham and Women's Hospital
R. Eugene Ramsay - Ochsner Health System
Angela K. Birnbaum - University of Minnesota
Publication Details: Journal of clinical pharmacology, Vol.53(3), pp.276-284
Publisher: Blackwell Publishing Ltd
Number of pages: 9
Identifiers: 9925575408331
Academic Unit: Prince Sattam Bin Abdulaziz University
Language: English
Resource Type: Journal article