Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

Kumar Gaurav; Sanu Arora; Paula Silva; Javier Sanchez-Martin; Richard Horsnell; Liangliang Gao; Gurcharn S. Brar; Victoria Widrig; W. John Raupp; Narinder Singh; Shuangye Wu; Sandip M. Kale; Catherine Chinoy; Paul Nicholson; Jesus Quiroz-Chavez; James Simmonds; Sadiye Hayta; Mark A. Smedley; Wendy Harwood; Suzannah Pearce; David Gilbert; Ngonidzashe Kangara; Catherine Gardener; Macarena Forner-Martinez; Jiaqian Liu; Guotai Yu; Scott A. Boden; Attilio Pascucci; Sreya Ghosh; Amber N. Hafeez; Tom O'Hara; Joshua Waites; Jitender Cheema; Burkhard Steuernagel; Mehran Patpour; Annemarie Fejer Justesen; Shuyu Liu; Jackie C. Rudd; Raz Avni; Amir Sharon; Barbara Steiner; Rizky Pasthika Kirana; Hermann Buerstmayr; Ali A. Mehrabi; Firuza Y. Nasyrova; Noam Chayut; Oadi Matny; Brian J. Steffenson; Nitika Sandhu; Parveen Chhuneja; Evans Lagudah; Ahmed F. Elkot; Simon Tyrrell; Xingdong Bian; Robert P. Davey; Martin Simonsen; Leif Schauser; Vijay K. Tiwari; H. Randy Kutcher; Pierre Hucl; Aili Li; Deng-Cai Liu; Long Mao; Steven Xu; Gina Brown-Guedira; Justin Faris; Jan Dvorak; Ming-Cheng Luo; Ksenia Krasileva; Thomas Lux; Susanne Artmeier; Klaus F. X. Mayer; Cristobal Uauy; Martin Mascher; Alison R. Bentley; Beat Keller; Jesse Poland; Brande B. H. Wulff

doi:10.1038/s41587-021-01058-4

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Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

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Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement

Kumar Gaurav, Sanu Arora, Paula Silva, Javier Sanchez-Martin, Richard Horsnell, Liangliang Gao, Gurcharn S. Brar, Victoria Widrig, W. John Raupp, Narinder Singh, …

Nature biotechnology, Vol.40(3), p.422

01/03/2022

DOI: https://doi.org/10.1038/s41587-021-01058-4

PMID: 34725503

Abstract

Biotechnology & Applied Microbiology

Life Sciences & Biomedicine

Science & Technology

Aegilops tauschii, the diploid wild progenitor of the D subgenome of bread wheat, is a reservoir of genetic diversity for improving bread wheat performance and environmental resilience. Here we sequenced 242 Ae. tauschii accessions and compared them to the wheat D subgenome to characterize genomic diversity. We found that a rare lineage of Ae. tauschii geographically restricted to present-day Georgia contributed to the wheat D subgenome in the independent hybridizations that gave rise to modern bread wheat. Through k-mer-based association mapping, we identified discrete genomic regions with candidate genes for disease and pest resistance and demonstrated their functional transfer into wheat by transgenesis and wide crossing, including the generation of a library of hexaploids incorporating diverse Ae. tauschii genomes. Exploiting the genomic diversity of the Ae. tauschii ancestral diploid genome permits rapid trait discovery and functional genetic validation in a hexaploid background amenable to breeding. Exploring the diversity of the wild progenitor of the wheat D subgenome allows for rapid trait discovery.

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Title: Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement
Creators - without role: Kumar Gaurav - Norwich Research Park
Sanu Arora - Norwich Research Park
Paula Silva - Kansas State University
Javier Sanchez-Martin - University of Zurich
Richard Horsnell - National Institute of Agricultural Botany
Liangliang Gao - Kansas State University
Gurcharn S. Brar - University of Saskatchewan
Victoria Widrig - University of Zurich
W. John Raupp - Kansas State University
Narinder Singh - Kansas State University
Shuangye Wu - Kansas State University
Sandip M. Kale - Leibniz Institute of Plant Genetics and Crop Plant Research
Catherine Chinoy - Norwich Research Park
Paul Nicholson - Norwich Research Park
Jesus Quiroz-Chavez - Norwich Research Park
James Simmonds - Norwich Research Park
Sadiye Hayta - Norwich Research Park
Mark A. Smedley - Norwich Research Park
Wendy Harwood - Norwich Research Park
Suzannah Pearce - Norwich Research Park
David Gilbert - Norwich Research Park
Ngonidzashe Kangara - Norwich Research Park
Catherine Gardener - Norwich Research Park
Macarena Forner-Martinez - Norwich Research Park
Jiaqian Liu - Nanjing Agricultural University
Guotai Yu - Norwich Research Park
Scott A. Boden - Norwich Research Park
Attilio Pascucci - Norwich Research Park
Sreya Ghosh - Norwich Research Park
Amber N. Hafeez - Norwich Research Park
Tom O'Hara - John Innes Ctr, Norwich Res Pk, Norwich, Norfolk, England
Joshua Waites - Norwich Research Park
Jitender Cheema - Norwich Research Park
Burkhard Steuernagel - Norwich Research Park
Mehran Patpour - Aarhus University
Annemarie Fejer Justesen - Aarhus University
Shuyu Liu - Texas A&M AgriLife Res, Amarillo, TX USA
Jackie C. Rudd - Texas A&M AgriLife Res, Amarillo, TX USA
Raz Avni - Tel Aviv University
Amir Sharon - Tel Aviv University
Barbara Steiner - University of Natural Resources and Life Sciences, Vienna
Rizky Pasthika Kirana - University of Natural Resources and Life Sciences, Vienna
Hermann Buerstmayr - University of Natural Resources and Life Sciences, Vienna
Ali A. Mehrabi - Ilam University
Firuza Y. Nasyrova - Academy of Sciences of the Republic of Tajikistan
Noam Chayut - Norwich Research Park
Oadi Matny - University of Minnesota
Brian J. Steffenson - University of Minnesota
Nitika Sandhu - Punjab Agricultural University
Parveen Chhuneja - Punjab Agricultural University
Evans Lagudah - Commonwealth Scientific and Industrial Research Organisation
Ahmed F. Elkot - Agricultural Research Center
Simon Tyrrell - Norwich Research Park
Xingdong Bian - Norwich Research Park
Robert P. Davey - Norwich Research Park
Martin Simonsen - Qiagen
Leif Schauser - Qiagen
Vijay K. Tiwari - University of Maryland, College Park
H. Randy Kutcher - University of Saskatchewan
Pierre Hucl - University of Saskatchewan
Aili Li - Institute of Crop Sciences
Deng-Cai Liu - Sichuan Agr Univ, Triticeae Res Inst, Chengdu, Peoples R China
Long Mao - Institute of Crop Sciences
Steven Xu - Edward T. Schafer Agricultural Research Center
Gina Brown-Guedira - Agricultural Research Service
Justin Faris - Edward T. Schafer Agricultural Research Center
Jan Dvorak - University of California, Davis
Ming-Cheng Luo - University of California, Davis
Ksenia Krasileva - University of California, Berkeley
Thomas Lux - Helmholtz Zentrum München
Susanne Artmeier - Plant
Klaus F. X. Mayer - Plant
Cristobal Uauy - Norwich Research Park
Martin Mascher - Leibniz Institute of Plant Genetics and Crop Plant Research
Alison R. Bentley - National Institute of Agricultural Botany
Beat Keller - University of Zurich
Jesse Poland - Kansas State University
Brande B. H. Wulff - Norwich Research Park
Publication Details: Nature biotechnology, Vol.40(3), p.422
Publisher: NATURE PORTFOLIO
Number of pages: 27
Grant note: BB/N019113/1 / BBSRC-Embrapa Newton Fund 1822162 / US National Science Foundation (NSF) Industry-University Cooperative Research Center (IUCRC) Award; National Science Foundation (NSF) Fulbright Scholars Program John Innes Foundation BBS/E/J/000PR8000 / UK Research and Innovation-BBSRC National Capability grant 310030B_182833 / Swiss National Science Foundation; Swiss National Science Foundation (SNSF); European Commission 4105-00022B / Innovation Fund Denmark award Consejo Nacional de Ciencia y Tecnologia scholarship CAAS-DRW202002 / Knowledge Innovation Program of Chinese Academy of Agricultural Sciences BB/PPR1740/1 / BBSRC; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC) 91731305; 31661143007 / National Science Foundation of China; National Natural Science Foundation of China (NSFC) 20180095 / Agriculture Development Fund of the Saskatchewan Ministry of Agriculture project Austrian Agency for International Cooperation in Education and Research (OeAD-GmbH) BB/I002561/1 / UK Biotechnology and Biological Sciences Research Council (BBSRC) Wheat Improvement Strategic Programme; UK Research & Innovation (UKRI); Biotechnology and Biological Sciences Research Council (BBSRC) JIC International Scholarships 332408563 / Newton-Mosharafa Fund Jewish National Fund of Australia JIC Science For Africa Initiative ERC-2016-STG-716233-MIREDI / European Research Council; European Research Council (ERC); European Commission BT/PR30871/BIC/101/1159/2018; BT/IN/Indo-UK/CGAT/14/PC/2014-15 / Department of Biotechnology, India; Department of Biotechnology (DBT) India ASEA-UNINET Phase II IUCRC at the KSU Center for Wheat Genetic Resources DP210103744 / The Royal Society award Saskatchewan Wheat Development Commission Universita di Bologna scholarship 30718 / Egypt-UK Newton-Mosharafa Institutional Links award BBS/E/T/000PR9817 / BBSRC Earlham Institute Strategic Programme B65336 / Kansas Wheat Commission 674964 / European Union's Horizon 2020 research and innovation programme Marie Skodowska-Curie grant BBS/E/T/000PR9814 / BBSRC National Capability award JIC Institute Development Grant 2Blades Foundation BB/M011216/1 / UKRI BBSRC Norwich Research Park Biosciences Doctoral Training Partnership scholarship BB/P016855/1 / BBSRC Designing Future Wheat Institute Strategic Programme 2020-67013-31460 / National Institute of Food and Agriculture-USDA awards Alberta Wheat Development Commission Manitoba Crop Alliance United States Department of Agriculture (USDA) FAIN 1339389; IOS-1238231 / US-NSF; National Science Foundation (NSF) Bayer; Bayer AG Ministry of Education and Culture of the Republic of Indonesia; Ministry of Research and Technology of the Republic of Indonesia (RISTEK) Science and Technology Development Fund; Science and Technology Development Fund (STDF)
Identifiers: 9944814108331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article