Abstract
Currently, there is no universally accepted method to evaluate liver function post-orthotopic liver transplant (OLTx) and there are no early surrogate function markers to assess the impact of perioperative interventions in trial settings.
In total, 495 patients were included in the study. On multivariate analysis, PTLF score, defined as normal (score <4) or dysfunctional (score ≥ 4), was the only significant variable for determining significant complications (P=0.014) and graft survival (P=002) during the perioperative period.
In total, 495 patients were included in the study. On multivariate analysis, PTLF score, defined as normal (score <4) or dysfunctional (score ≥ 4), was the only significant variable for determining significant complications (P=0.014) and graft survival (P=002) during the perioperative period.
PTLF score shows promise as an early surrogate marker of post-orthotopic liver transplantation mortality and morbidity by providing results within the first 7 days post-transplantation. PTLF score can potentially be used as a tool to assess the impact of perioperative interventions by predicting long-term outcomes early in the clinical course of transplant patients.