Abstract
Anastomotic leak (AL) is a serious complication of intestinal surgery with various predisposing factors. This study aims to assess several risk factors associated with AL after small intestinal and colonic anastomoses through a multivariate analysis. Two hundred twenty-four patients (126 males) with intestinal anastomosis of a median age of 44 years were reviewed. Independent factors associated with AL were male gender (OR = 2.59,
P
= 0.02), chronic liver disease (CLD) (OR = 8.03,
P
< 0.0001), more than one associated comorbidity (OR = 5.34,
P
= 0.017), anastomosis conducted as emergency (OR = 2.73,
P
= 0.012), colonic anastomosis (OR = 2.51,
P
= 0.017), preoperative leukocytosis (OR = 2.57,
P
= 0.015), and intraoperative blood transfusion (OR = 2.25,
P
= 0.037). Predicative factors significantly associated with AL were male gender, CLD, multiple comorbidities, emergent anastomoses, colonic anastomoses, preoperative leukocytosis, and intraoperative blood transfusion.