Sign in
Back
Prenylbicyclogermacrane diterpenoids from the formosan soft coral Nephthea pacifica
Journal article   Peer reviewed

Prenylbicyclogermacrane diterpenoids from the formosan soft coral Nephthea pacifica

Ali A H El-Gamal, Shang-Kwei Wang, Chang-Feng Dai, I-Gin Chen and Chang-Yih Duh
Journal of natural products (Washington, D.C.), Vol.68(1), pp.74-77
01/01/2005
DOI: https://doi.org/10.1021/np040160e
PMID: 15679321

Abstract

Animals Anthozoa - chemistry Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacology Drug Screening Assays, Antitumor Leukemia P388 Mice Molecular Structure Nuclear Magnetic Resonance, Biomolecular Taiwan
Ten new prenylbicyclogermacrane diterpenoids, pacificins A-J (1-10), were isolated from the methylene chloride solubles of the Formosan soft coral Nephthea pacifica. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

Metrics

1 Record Views

Details