Abstract
A series of twelve metal complexes with 2-hydroxy-N'-3-(hydroxyimino)butan-2-ylidene) benzohydrazide ligand was synthesized and characterized using elemental analyses, IR, NMR, Mass, and UV-Visible spectra. The ligand behaves either as neutral bidentate, monobasie tridentate, monobasic dibasic tetradentate ligand bonded covalenacy via deprotonated oxamato and enolic carbonyls groups as well as coordinated via the azomethine and oxime nitrogen atoms. The synthesized complexes possess a square-pyramidal re-pyramidal geometry as in complexes (2-5) and (13) or octahedral as in complex (7-12), while complex (6) has a tetrahedral geometry. The copper(II) complexes (2-5) ESR spectra confirmed that they have a square pyramidal geometry with a dx2-y2 ground state. The synthesized complexes demonstrate a high cytotoxicity against A.I niger and the best one was [Z n(H2L)2] (11) with 84% in compare with Nystatin as a positive control, a moderate activity against E. coli and B. subtilis with 77 and 88% respectively for [Ni(H2L)2] (7) as a best result compare with the positive control Amoxicillin.