Abstract
Acacia honey is characterized by high nutritional, antioxidant, antibacterial and immuno-modulatory values. This work investigated the presence of short and cyclic peptides in Acacia and Ziziphus honey samples. Acacia honey samples (
and
) and three Ziziphus honeys (
) were screened for their short and cyclic peptide contents using the LC-MS and the chemical structure databases. Moreover, the total protein content was determined using the Bradford method. The
honey contained three short peptides; HWCC, DSST, and ECH, and the
honey sample contained five short peptides and one cyclic peptide. The short peptides of the
honey were Ac-GMGHG-OH (Ac-MGGHG-OH), Boc-R(Aloc)2-C(Pal)-OH, H-C (1)-NEt2·H-C (1)-NEt2, APAP (AAPP), and GAFQ (deamino-2-pyrid-4-yl-glycyl-
-alanyl-
-norvalyl-
-asparagine). The cyclic peptide of the
honey was
[Aad-RGD-
-F] (
[Aad-Arg-Gly-Asp-
-Phe]). The Ziziphus honey was characterized by the presence of either Almiramide B or Auristatin-6-AQ.
,
and Ziziphus honeys are characterized by the presence of short and cyclic peptides which may contribute to their medicinal values.