Abstract
The global prevalence of DM is steadily increasing. Depression in patients with diabetes is more prevalent than in the general population. There is good evidence. The bidirectional link can be between diabetes and depression. The chronic nature of the illness and its various consequences can lead to depressive diabetes patients, while increased counter-rulatory hormones can cause the development of diabetic syndromes. Social and environmental variables which influence self-care burden patients and their families substantially. It can lead to depression. Depressed people with diabetes also may experience poor health, inadequate income, stigma and a lack of social support. The aim of the present study is to summarize previously estimated prevalence of depression in patients diagnosed with T2DM, and to identify sociodemographic, clinical and psychological factors associated with the occurrence of depression in diabetic patients in Saudi Arabia and worldwide.