Prevention of the luteolytic action of oxytocin in the goat by inhibition of prostaglandin synthesis

R.G. Cooke; A.M. Homeida; Universite de Paris-11, Orsay (France)

doi:10.1016/0093-691X(83)90070-5

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Prevention of the luteolytic action of oxytocin in the goat by inhibition of prostaglandin synthesis

Journal article

Peer reviewed

Prevention of the luteolytic action of oxytocin in the goat by inhibition of prostaglandin synthesis

R.G. Cooke, A.M. Homeida and Universite de Paris-11, Orsay (France)

Theriogenology, Vol.20(3), pp.363-365

01/01/1983

DOI: https://doi.org/10.1016/0093-691X(83)90070-5

PMID: 16725852

Abstract

Oxytocin-induced luteolysis in goats was associated with significant increases in peripheral plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F 2α (PGFM). Oral administration of the prostaglandin (PG) synthetase inhibitor meclofenamic acid (lg/day) prevented both the luteolytic action of oxytocin and the increase in PGFM concentrations. These results confirm that the luteolytic effect of oxytocin is mediated via the production and release of PGF 2α.

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Title: Prevention of the luteolytic action of oxytocin in the goat by inhibition of prostaglandin synthesis
Creators - without role: R.G. Cooke - University of Liverpool
A.M. Homeida - University of Liverpool
Universite de Paris-11, Orsay (France)
Publication Details: Theriogenology, Vol.20(3), pp.363-365
Publisher: Elsevier Inc
Identifiers: 9920130408331
Academic Unit: King Faisal University
Language: English
Resource Type: Journal article