Abstract
Background: Adenocarcinoma of the duodenum is a rare tumor. It represents about 0.35% of gastrointestinal cancers. It poses a problem of late diagnosis and management. The only curative treatment is surgery. The aim of our work was to study the epidemiological, clinical, endoscopic and therapeutic characteristics of this tumor in the region of Marrakech (Morocco).
Materials and Methods: We conducted a retrospective descriptive study of adenocarcinoma of the duodenum collected in gastroenterology department of CHU Mohamed VI Marrakech (Morocco).
Results: We collected eight cases of duodenal adenocarcinoma, which accounts for 0.3% of all gastrointestinal cancers diagnosed over the same period. The sex ratio was 3. Revealing symptoms was represented mainly by epigastric pain, postprandial vomiting late, gastrointestinal bleeding and an alteration of general condition. The tumor was located at the first (DI) and second (DII) duodenum in 3 cases, the DII in 5 cases. She was stenosis in 1 case. The staging revealed liver and lymph node metastasis in 4 cases. The pancreaticoduodenectomy was indicated in 4 cases and palliative chemotherapy in 4 cases.
Conclusion: Our series was characterized by the young age of patients, predominantly male, predominant localization at DII, and the advanced stage of the tumor at diagnosis.