Abstract
A 27-year-old primigravid patient presented with severe abdominal pain during the 10th week of gestation. Blood test results, including those of lipase and liver enzymes, were unremarkable. However, doppler ultrasonography of the abdomen revealed left portal vein thrombosis. Therapeutic enoxaparin was initiated, resolving the pain. At week 25 of gestation, the patient went into labor and delivered, vaginally, a single, live male infant. The newborn died within one week. Postpartum, she underwent further investigation to identify the cause of portal vein thrombosis. A thrombophilia workup revealed low protein S activity. This case highlights the importance of performing a thrombophilia workup in women with portal vein thrombosis during pregnancy.