Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma

Latifa Chachi; Mahnaz Abbassian; Adelina Gavrila; Abdulrahman Alzahrani; Omar Tliba; Peter Bradding; Andrew J. Wardlaw; Christopher Brightling; Yassine Amrani

doi:10.1111/all.13003

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Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma

Journal article

Peer reviewed

Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma

Latifa Chachi, Mahnaz Abbassian, Adelina Gavrila, Abdulrahman Alzahrani, Omar Tliba, Peter Bradding, Andrew J. Wardlaw, Christopher Brightling and Yassine Amrani

Allergy (Copenhagen), Vol.72(1), pp.126-136

01/2017

DOI: https://doi.org/10.1111/all.13003

PMCID: PMC5154839

PMID: 27501780

Abstract

airway smooth muscle

corticosteroid insensitivity

corticosteroid receptor

protein phosphatase

receptor phosphorylation

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Title: Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma
Creators - without role: Latifa Chachi - University of Leicester
Mahnaz Abbassian - Thomas Jefferson University
Adelina Gavrila - University of Leicester
Abdulrahman Alzahrani - University of Leicester
Omar Tliba - Thomas Jefferson University
Peter Bradding - University of Leicester
Andrew J. Wardlaw - University of Leicester
Christopher Brightling - University of Leicester
Yassine Amrani - University of Leicester
Publication Details: Allergy (Copenhagen), Vol.72(1), pp.126-136
Identifiers: 9912006108331
Academic Unit: Al Baha University
Language: English
Resource Type: Journal article