Abstract
Background Alzheimer's disease (AD) is a major public health problem and represents commonest form of dementia that affects many aspects of brain functions and contributes to 60-70% of dementia cases. No study has been conducted in Saudi Arabia to measure the prevalence of AD. However, approximately there are at least 50,000 patients in Saudi Arabia based on an expert's estimation.Public knowledge and awareness about Alzheimer's disease are crucial for early diagnosis and management. Objective To investigate the public's knowledge and attitudes toward Alzheimer's disease in Aseer region. Subject and methods Cross-sectional study has employed an electronic online, semi-structured, and self-administered questionnaire, randomly distributed among participants. The questions included sociodemographics, attitudes, and knowledge panels toward Alzheimer's disease based on Alzheimer's Disease Knowledge Scale (ADKS). Results The study included 1374 participants with a mean age 33 +/- 11 years (ages18-70). The majority of the participants (77%) had no family history with Alzheimer's disease. Less than 50% of the questions were answered correctly and the mean knowledge score was 10.77 +/- 5.11. The results revealed that young-aged participants, females, and those having a family history of the disease, have significantly (P< 0.05) better AD-related knowledge. Conclusion The study revealed an inadequate AD-related knowledge as indicated by the low mean knowledge score. However, participants have demonstrated a positive attitude toward AD patients. More educational programs are required to enhance their awareness and knowledge about AD.