Abstract
-[ReBr(CO)
(L
)] L
= 1-ethyl-2-(pyridin-2-yl)benzimidazole (1) and L
= 1-[(pyridin-2-yl) benzimidazole]-propyl-sulfonic acid (2),
-[Re
Br
(CO)
L
] (3) L
= 1,1'-(hexane-1,6-diyl)bis[2-(pyridin-2-yl)1
-benzimidazole] and
-[ReBr(CO)
(L
-κ
N
N
)] (L
= 2,6-bis(benzimidazol-2'-yl)pyridine (4) and L
= 2,6-bis(1-ethyl-benzimidazol-2'-yl)pyridine (5) were synthesized and fully characterized using different spectrocopic and analytical tools. The spectrocopic data showed coordination of L
to
-ReBr(CO)
the benzimidazole and pyridine N-atoms. For 4 and 5, the absence of a two-fold axis of symmetry for L
in the
H NMR spectra reflect the κ
N
,N
mode of coordination. The electronic properties of 1-5 were investigated by time-dependent density functional theory calculations in the singlet and triplet states. The ligands and their Re(i) complexes were assessed for their potential antimicrobial activity. Compound 5 was screened against non-malignant cell line (noncancerous human embryonic kidney cell line (HEK293)) as well as evaluated for its blood compatibility.