Abstract
The protected 2-formyl-
L
-arabinal
2
reacted with thiourea and cyanamide in the presence of sodium hydride to afford via ring transformations the 5-[1
R
,2
S
-1,2-bis(benzyloxy)-3-hydroxypropyl]-1,2-dihydropyrimidines
3
and
4
, respectively. Similarly, treatment of
2
with 3-amino-2
H
-1,2,4-triazole yielded 6-[1
R
,2
S
-1,2-bis(benzyloxy)-3-hydroxypropyl][1,2,4]-triazolo[1,5-
a
]pyrimidine (
5
).