Abstract
Background and aim of the work: The incidence of Ulcerative Colitis is rising globally, but so are the quality of medical care and the range of UC treatment choices. This study compared the quality of life for UC patients who underwent surgical treatment versus medical treatment to discover which is superior and to offer data for clinical use. Methods: A retrospective cohort study at King Abdulaziz University Hospital in Jeddah, Saudi Arabia was performed on a total of 352 UC patients who required hospitalization between January 2010 and October 2022 were classified based on surgical treatment. The sample size 184 was calculated using 5% margin error, 95% confidence interval. First class composed of 18 out of 34 surgically treated patients, second class composed of 166 out of 318 medically treated patients (non-surgical), QoL was measured using SF-36. Results: A total of 184 individuals with UC were included in the study; 90.2% of them were receiving medical care and 9.8% underwent surgery. Quality of life was significantly higher among medically treated patients for emotional wellbeing (64.7% +/- 21.9%). Additionally, those who received medical treatment had much better overall health (56.4% 18.3). Additionally, compared to 33.3% of patients receiving surgical treatment, 44% of those receiving medicinal treatment had an overall high quality of life (P=.024). Conclusion: In terms of symptoms, flare-ups and quality of life our study showed that the medical treatment options considered to improved management of the condition. Asthma, hypertension, hyperlipidemia and diabetes mellitus were found to be unrelated according to the study.