Abstract
The primary goal of this study was to assess the quantitative and differential measurements of aberrant fine needle aspiration cytology of breast lesions in Sudanese women. In Khartoum state, a descriptive retrospective study was undertaken to investigate FNAC of atypical breast lesions. The research was carried out between February 2021 and January 2022. Patients of all ages were included as participants. A total of 75 breast FNAC preparations were enrolled, covering all specimens during the study's duration. The findings were evaluated and debated with a number of cytopathologists. There is a correlation between the types of lesions and age, site of appearance, mass size, form, and texture. Moreover, lesions are more common in patients aged 30-39 (p value =0.000). The lesion spread was unilateral (p value =0.001), which was the most common, and the size of the lesion was between 5- 10 cm. Because the majority of the lesions were solid, as was the tissue of the mass, the regular immobile mass was the most common in the sample size (p value =0.000). The female participants in the study are mostly middle-aged women. The most prevalent benign diseases in this study are fibrocystic and fibroadenoma, with ductal cell carcinoma being the only malignant tumor. Malignant tumors were associated with abnormalities in the N/C ratio, nuclear size, and chromatin pattern.