Abstract
The quantum dots (QDs) are a special class of inorganic (QDs, <10 nm) structures, having an exceptional place in quantum nanotechnology due to their outstanding photo physical properties. These QDs can be applied easily to any existing technologies and plays an important role in various biological entities. To keep this view, the present work was designed the formation of QDs of SnO2 via solution route and the QDs were applied on myoblast (C2C12) cancer cells to check their reactivity at dissimilar quantities of QDs (200 ng/mL, 5 mu g/mL and 10 pg/mL) at altered cultivation periods (24, 48 & 72 h) of cells. % viability was calculated via MTT assay whereas the morphological organization of dead and live cells and their effect with QDs were also observed via confocal microscopy and it confirmed that as the heating/cultivation increases, mass of cells were decreases. Including these, the apoptosis caused due to QDs, were also checked via RT-PCR and the obtained data reveals that the up-regulation was observed in genes with treatment of C2C12 in occurrence of SnO2 QDs. The analytical study were exhibited via statistical analysis for cells and QDs. Including this, molecular docking was completed to know the mechanistic approach and action of QDs in cells.