Abstract
Objective: We aimed to compare the Pterygium recurrence rate followed by the intraoperative use of Conjunctival Auto-graft and Mitomycin - C.
Methodology: Our RCT (Randomized Controlled Trial) held at Ophthalmology Department of Allied Hospital, Faisalabad from September 2016 to April 2017 on a total of 130 patients. We divided the 130 patients into two groups through random distribution. Group - I had 65 patients treated with intraoperative Mitomycin - C; whereas, Group - II also had 65 patients treated with Conjunctival Auto-graft. Each group had an equal number of patients but managed differently with a six-month duration follow-up in order to observe the recurrence signs and symptoms in the patients.
Results: Reported reoccurrences in Group - I were ten (15.3%); whereas, in Group - II only two occurrences (3%) in the overall follow-up time period. Significant variation was in both groups as reflected in P-value (< 0.05); which implies better research outcomes in Group - II (Conjunctival Auto-graft) in terms of a success rate than Group - I (Mitomycin - C).
Conclusion: In visually significant pterygium cases, there is a decreased reoccurrence in the pterygium surgery with the application of Conjunctival Auto-graft than Group - I (Mitomycin - C) adjuvant.