Abstract
Introduction: studies recently were talking about ABO blood groups and whether it's linked to some diseases or not. Cholelithiasis had a room between these studies too, but different studies have shown different results. However, there is no case-control study was done to confirm the relation rather than finding an association.
Methods: An observational analytical case-control study had been carried out in King Fahad Hospital, Al-Madina, Kingdom of Saudi Arabia. The study had been conducted through the year 2018. Both descriptive and inferential statistics had been conducted.
Results: Majority of the participants were female as 266 (63.2%) while 155 (36.8%) were males. Out of these numbers, 218 (51.8%) were aged 31 -50 years old. Blood type O was the highest among participants with 194 (46.1%), followed by blood type A with 119 (28.3%), next was blood type B with 90 (21.4%) and with a relatively low number of blood type AB as 18 (04.3%). There was a significant relationship found in the age group and blood type group.
Conclusion: The findings of this study indicated that those patients in the middle age group with blood type O will likely to have cholelithiasis. Although more investigation is needed to support this claim, however, since the majority of our sample size was blood type O, we cannot generalize at this stage that blood group O is one of the major risk factors of cholelithiasis.