Abstract
Introduction: antibiotic-resistance is considered one of the main public health problems. The leading cause for antimicrobial resistance is the unsuitable usage of antimicrobials.
Methodology: The methodology includes searching PubMed, using the key word (topical antibiotic) AND (resistance) , the search was limited to include only clinical trials during the last 10 years.
Results: Many infections don't need using antimicrobials systemically and can be treated with a topical antimicrobial. Topical antibiotics has some side effects and probable resistance has developed against it. As a result, the researchers start searching for new topical antimicrobials to decrease the bacterial resistance.
Conclusion:
Bacterial resistance lead to many negative outcomes, this resistance can occur by using systemic or topical antibiotics, so it is important to use antibiotics only when needed and the patients should follow the recommendations that were given by the health care providers. It is important to increase the awareness about the bacterial resistance.