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Reaction of alkyl mercaptoacetates with N-cyanoimidates, N-acylimidates and N-ethoxycarbonylimidates: Synthesis of alkoxycarbonylthiazoles
Journal article   Peer reviewed

Reaction of alkyl mercaptoacetates with N-cyanoimidates, N-acylimidates and N-ethoxycarbonylimidates: Synthesis of alkoxycarbonylthiazoles

K Dridi, M L EL Efrit and H Zantour
Phosphorus, sulfur, and silicon and the related elements, Vol.134, pp.407-412
01/03/1998
DOI: https://doi.org/10.1080/10426509808043617

Abstract

Chemistry Chemistry, Inorganic & Nuclear Chemistry, Organic Physical Sciences Science & Technology
N-cyano, N-acyl and N-ethoxycarbonyl imidates are well known as versatile reagents in the synthesis of heterocyclic compounds. These imidates react with alkyl mercaptoacetates, in basic medium, to lead to the formation of 4-amino-5-alcoxycarbonylthiazoles, 5-alcoxycarbonylthiazoles and 5-alcoxycarbonyl-4-hydroxythiazoles.

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