Abstract
The reactivity of few novel high-spin Fe(II) complexes of Schiff base ligands derived from 2-hydroxynaphthaldehyde and some variety of amino acids with the OH- ion has been examined in an aqueous mixture at the temperature range from 10 to 40 degrees C. Based on the kinetic investigations, the rate law and a plausible mechanism were proposed and discussed. The general rate equation was suggested as follows: rate = k(obs)[complex], where k(obs.) = k(1) + k(2)[OH-]. Base-catalyzed hydrolysis kinetic measurements imply pseudo-first-order doubly stage rates due the presence of mer- and fac-isomers. The observed rate constants k(obs) are correlated with the effect of substituent R in the structure of the ligands. From the effect of temperature on the rate base hydrolysis reaction, various thermodynamic parameters were evaluated. The evaluated rate constants and activation parameters are in a good agreement with the stability constants of the investigated complexes. Moreover, the reactivity of the investigated complexes toward DNA was examined and found to be in a good agreement with the reported binding constants. (C) 2014 Wiley Periodicals, Inc.