Abstract
Macrocyclic compounds can be easily sustained into varied functionality, which has recently famed them as an individual supramolecular entity. Owing to their tenable non-covalent interactions or dynamic covalent bonding, these macrocyclic formulations have contemporaneously inhibited and controlled the progression of infectious diseases and cancers. Macrocyclic supramolecular assemblies have been fabricated for staging the medicinal accuracy of different therapies as well as diagnostic pathways. This mini-review, therefore, focuses on the design of a hierarchical assembly process at themolecular level of chemical composition and presents interesting illustrations of supramolecular assembled structural motifs as new cancer diagnostic and therapeutic options.