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Regioselective palladium-catalyzed Suzuki-Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines
Journal article   Peer reviewed

Regioselective palladium-catalyzed Suzuki-Miyaura coupling reaction of 2,4,6-trihalogenopyrido[2,3-d]pyrimidines

Yassine Riadi, Said Lazar and Gerald Guillaumet
Comptes rendus. Chimie, Vol.22(4), pp.294-298
01/04/2019
DOI: https://doi.org/10.1016/j.crci.2019.01.006

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
An effective, regioselective, and novel strategy to the access of 2,4,6-trisubstituted pyrido [2,3-d]pyrimidines is developed from the corresponding 2,4,6-trihalogenopyrido[2,3-d] pyrimidine through a Suzuki-Miyaura coupling reaction involving a novel regioselective halogen discrimination. (C) 2019 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.

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