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Regioselective synthesis and biological evaluation of novel bis(2-chloroquinolines)
Journal article   Peer reviewed

Regioselective synthesis and biological evaluation of novel bis(2-chloroquinolines)

K. Rajesh, B. Palakshi Reddy, S. Sarveswari and V. Vijayakumar
Research on chemical intermediates, Vol.39(9), pp.4259-4267
01/11/2013
DOI: https://doi.org/10.1007/s11164-012-0942-x

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Reaction of substituted 2,4-dichloroquinolines with bisphenol A in the presence of K2CO3 leads to novel bis(2-chloroquinolines) with high regioselectivity. All the synthesized compounds were characterized by use of spectral data. Preliminary evaluation of in-vitro antibacterial activity against a variety of Gram-positive and Gram-negative organisms was also conducted.

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