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Regioselective synthesis of novel 2-chloroquinoline derivatives of 1,4-dihydropyridines
Journal article   Peer reviewed

Regioselective synthesis of novel 2-chloroquinoline derivatives of 1,4-dihydropyridines

K. Rajesh, P. Iniyavan, S. Sarveswari and V. Vijayakumar
Research on chemical intermediates, Vol.40(5), pp.1851-1866
01/05/2014
DOI: https://doi.org/10.1007/s11164-013-1085-4

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Highly regioselective reaction of some substituted 2,4-dichloroquinolines with symmetrical 1,4-dihydropyridines, leading to novel quinoline derivatives of DHPs, has been achieved in the presence of powdered K2CO3, as a mild and efficient base, at moderate temperature. All the synthesized compounds were characterized by use of IR, NMR, and mass spectral data.

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