Abstract
Relapsing polychondritis (RPC) is a rare multisystem autoimmune disease that has been a challenging diagnosis given its rarity and vague presentation. In this article we report a rare association between RPC and ulcerative colitis. We also present a comprehensive review that included the different associations and manifestations of RPC, the evolution of the diagnostic criteria proposed by different authors and the conventional modalities of therapy highlighting the use of biologic agents in such a rare condition.