Abstract
Fourteen pregnant women between 37 and 41 weeks' gestational age, who subsequently were delivered of healthy newborn infants, were studied to examine the effects of spontaneous changes in fetal heart rate on the flow-velocity waveforms in the umbilical artery. The women were in active labor and under epidural anesthesia at the time Doppler measurements were made. There was a significant positive relationship between end-diastolic flow velocity and fetal heart rate. The umbilical artery peak-systolic/end-diastolic ratio was best correlated with the negative reciprocal transformation of the instantaneous fetal heart rate value and end-diastolic flow velocity. No significant correlation was found between fetal heart rate, umbilical artery peak-systolic/end-diastolic ratio, and peak-systolic flow velocity. An upper limit of 3.0 for a normal umbilical artery peak-systolic/end-diastolic ratio was acceptable only if the instantaneous fetal heart rate was ≥130 beats/min.