Abstract
In the present investigation, attempts were made to develop water/Transcutol/ethylene glycol (EG)/Capryol-90 green nanoemulsions for the removal of diclofenac sodium (DS) from aqueous solution. Various green nanoemulsions were prepared by oil phase titration method. Removal of DS was influenced by Capryol-90 & water concentrations, droplet size and viscosity. Based on lowest droplet size (43.6nm), lowest viscosity (81.4cP) and highest % removal (94.5%), the green nanoemulsion G5 containing 20% w/w of water, 50% w/w of surfactant mixture and 30% w/w of Capryol-90 was selected as an optimized formulation for the removal of DS from aqueous solution.
•Water-in-oil green nanoemulsions were prepared by oil phase titration method.•Stable formulations were utilized for removal of diclofenac sodium (DS).•Droplet size and viscosity of green nanoemulsions had greater impact on DS removal.•Around 94.5% of DS was removed by optimized green nanoemulsion.